InflammX is a targeted, research-based formulation to modulate inflammatory processes associated with chronic gut as well as whole body imbalance.
It is possible that stress, anxiety and depression could be a neuropsychiatric manifestation of a chronic inflammatory syndrome. And the primary cause of inflammation may be the dysfunction of the "gut-brain axis". Recent studies have shown that inflammation may be involved in the pathogenesis of depression. In fact, some research has demonstrated that depression as well as a variety of immune problems are frequently associated with gastrointestinal inflammations and autoimmune diseases as well as with other ailments in which chronic low-grade inflammation is a significant contributing factor.
Research suggests the primary cause of inflammation may be dysfunction of the "gut-brain axis." Your gut is literally your second brain -- created from the identical tissue as your brain during gestation -- and contains larger amounts of the neurotransmitter serotonin, which is associated with mood control.
It's important to understand that your gut bacteria are an active and integrated part of your body, and as such are heavily dependent on your diet and vulnerable to your lifestyle. If you consume a lot of processed foods and sweetened drinks, for instance, your gut bacteria are likely going to be severely compromised because processed foods in general will destroy healthy micro flora and sugars of all kinds feed bad bacteria and yeast, as well as promote systemic inflammation.
An increasing number of clinical studies have shown that treating gastrointestinal inflammation with probiotics, vitamin B, vitamin D and omega-3 fats may also improve depression symptoms and quality of life by attenuating pro-inflammatory stimuli to your brain.
When inflammation is active, it is highly self-perpetuating. Inflammatory cytokines travel throughout the body causing oxidating stress to the fragile machinery of the tissues and mitochondria, specifically. In the brain, inflammation serves to shunt the use of tryptophan toward production of anxiety-provoking chemicals like quinolinate, instead of toward serotonin and melatonin. They produce a replicable collection of symptoms called “sickness syndrome”, noted for its overlap with “depressive” symptoms: lethargy, sleep disturbance, decreased social activity, mobility, libido, learning, anorexia, and andhedonia. Psychiatric researchers have observed that patients with higher levels of inflammatory markers (like CRP) are less likely to respond to antidepressants, and more likely to respond to anti-inflammatories.
The gut immune system has the challenge of responding to pathogens while remaining relatively unresponsive to food antigens and the commensal micro flora. In the developed world, this ability appears to be breaking down, with chronic inflammatory diseases of the gut commonplace in the apparent absence of overt infections.
Approaches to chronic illnesses like depression, immune collapse, chronic fatigue and a variety of gut problems is a complex, non-specific symptom condition reflecting a state of bodily disharmony. It isn’t that you were born with bad genes or low serotonin. It is far more likely that you are experiencing an unhealthy inflammatory balance, driven by cortisol dysfunction, and stemming from a sick gut. Psychological factors most clearly predict the development of IBS symptoms after gastroenteritis but biological mechanisms also contribute towards the expression of symptoms.
Chronic fatigue syndrome (CFS) is a debilitating disease characterized by unexplained disabling fatigue and a combination of accompanying symptoms the pathology of which is incompletely understood. Many CFS patients complain of chronic gut dysfunction. In fact, patients with CFS are more likely to report a previous diagnosis of irritable bowel syndrome (IBS), a common functional disorder of the gut, and experience IBS-related symptoms.
InflammX is a targeted, research-based formulation to modulate inflammatory processes associated with chronic gut as well as whole body imbalance. It contains a combination of plant-based ingredients that are designed to work with your body (not against it) to inhibit inflammation without interfering with healthy functioning. An unhealthy diet (highly processed foods, low nutrients) and common food sensitivities may also influence GI health, inflammation, and related symptoms normalization of the IgA and IgM responses to translocated LPS may predict clinical outcome in CFS. The results support the view that a weakened tight junction barrier with subsequent gut-derived inflammation is a novel pathway in CFS as well as a variety of chronic diseases.
Vitamin A is commonly found in whole milk, liver, and some fortified foods. Beta-carotene is a provitamin found in carrots and many colorful vegetables that can be converted to vitamin A in the body. Vitamin A is an antioxidant. That means it protects against harmful substances in your body called free radicals, which can damage DNA and lead to cancer and other diseases. Vitamin A also has anti-inflammatory effects.
A lack of enough vitamin A has been linked to inflammation in the intestines, lungs, and skin.
For some people, taking vitamin A supplements could reduce the inflammation that contributes to conditions like inflammatory bowel disease, acne, and lung disease.
Vitamin B6
This member of the B vitamin family is plentiful in foods like beef, turkey, vegetables, and fish. Because vitamin B6 is water-soluble, the body is constantly ridding itself of it, so you need to restock it daily through diet.
Not getting enough vitamin B6 may increase the risk for heart disease. Studies have found that people who lack enough of this vitamin have high levels of C-reactive protein (CRP), a marker of inflammation that has been linked to heart disease.
A lack of vitamin B6 can increase inflammation associated with rheumatoid arthritis, leading to more joint damage. Yet in a vicious cycle, inflammation from rheumatoid arthritis can deplete the body's vitamin B6 stores. Taking vitamin B6 supplements daily can correct the deficiency, yet researchers say there's no conclusive evidence it will reduce inflammation too.
A pilot trial evaluating the effect of an inflammatory-modulating medical food in patients with fibromyalgia.
Dan Lukaczer, ND, Barbara Schiltz, RN, MS, CN, DeAnn J. Liska, PhD Functional Medicine Research Center, Gig Harbor, WA 98335, USA.
ABSTRACT
Fibromyalgia (FM) is a complex syndrome characterized by reproducible tenderness on palpation at specific anatomical sites, generalized stiffness and aching, and a variety of other systemic complaints. It is a common syndrome in the United States and one of the most common reasons for rheumatological referrals. Its etiology and pathogenesis are controversial. A variety of approaches have been used with a lack of consistent results. We present data suggesting that an approach using a complex medical food designed for clinical management of inflammatory conditions may also have a beneficial effect for FM patients. With this medical food, we observed a significant improvement in mental functioning (p<0.05) as assessed by the SF-36 questionnaire, a significant decrease in Tender Point Index (TPI; p<0.05), and a substantial improvement in grip strength and physical symptoms. Although the mechanism(s) underlying these observations is not understood, we propose that a number of activities may act synergistically to produce the noted improvements in FM patients treated with this Inflammatory-Modulating Medical Food.
