Epi-Gastro Enzyme Formula
Epi-Gastro Enzymes relieves heartburn, reflux and bloating caused by poor diet or gastric imbalances. It is an Ideal companion for holidays, business travel and a healthier alternative to acid-blockers and antiacids.
| Ingredients |
|---|
| Crataegus pinnatfida |
| Lonicera Japonica |
| Lindera Strychnifolia |
| Amylase |
| Protease |
| Lipase |
| Bromelain |
| Papain |
| Cellulase |
Other Ingredients: Vegetable cellulose (hypromellose); Vegetable Stearic Acid; Microcrystalline Cellulose and Vegetable Magnesium Stearate.
Does Not Contain: Wheat, gluten, soy, milk, eggs, fish, crustacean shellfish, tree nuts, peanuts
Epi-Gastro Enzyme Formula
60 x 500mg capsules
Actions
• Relieves reflux and heartburn and indigestion
• Increases gastric emptying time
• Increases pepsin and enhances protein absorption
• Helps increase gastric acid
Suggested Use:
to 3 capsules half hour prior to eating major meal. May be taken directly before a meal if irritation occurs.
Caution:
Care with internal 'cold' stomach.
Warning:
None noted.
Common Symptoms
Abdominal pain, bloating and belching after meals, chest pain, dark - tarry stools, fatigue, feeling of fullness after relatively small amounts of food, heartburn, indigestion, nausea or vomiting, especially vomiting blood & weight loss.
Alpha-amylase
Alpha-amylase begins the process of starch digestion. It takes starch chains and breaks them into smaller pieces with two or three glucose units. Two similar types of amylase are made in your body--one is secreted in saliva, where it starts to break down starch grains as you chew, and the other is secreted by the pancreas, where it finishes its job. Then, these little pieces are broken into individual glucose units by a collection of enzymes that are tethered to the walls of the intestine.
Trypsin
Trypsin is secreted into the intestine, where it acts to hydrolyse proteins into smaller peptides or amino acids. This is necessary for the uptake of protein in the food. Trypsin catalyses the hydrolysis of peptide bonds. The enzymatic mechanism is like all other serine.
Proteases
A catalytic triad serves to make the active site serine nucleophilic. This is achieved by modifying the electrostatic environment of the serine.
A lipase is a water-soluble enzyme that catalyses the hydrolysis of ester bonds in water-insoluble, lipid substrate is the main enzyme responsible for breaking down fats in the human digestive system, a lipase acts to convert triglyceride substrates found in oils from food to monoglycerides and free fatty acids.
Bromelain
Bromelain is a mixture of sulphur-containing protein digesting enzymes-called proteolytic enzymes or proteases-and several other substances in smaller quantities. Bromelain can be used in a vast array of medical conditions. It was first introduced in this area in 1957, and works by blocking some pro-inflammatory metabolites that accelerate and worsen the inflammatory process. It is an anti-inflammatory agent, and so can be used for sports injury, trauma, arthritis, and other kinds of swelling. Its main uses are athletic injuries, digestive problems, phlebitis, sinusitis, and aiding healing after surgery.
Papain
Papain is a cysteine protease (EC 3.4.22.2) present in papaya (Carica papaya), which is useful in tenderizing meat and other proteins. The mechanism by which it breaks peptide bonds involves deprotonation of Cys-25 by His-159. Asn-158 helps to orient the imidazole ring of His-159 to allow this deprotonation to take place. Cys-25 then performs a nucleophilic attack on the carbonyl carbon of a peptide backbone. This frees the amino terminal of the peptide, and forms a covalent acyl-enzyme intermediate.
Pepsin
Pepsin is a digestive protease (EC 3.4.23.1) released by the chief cells in the stomach that functions to degrade food proteins into peptides. Pepsin cleaves the 44 amino acids from pepsinogen to create more pepsin. Pepsin will digest up to 20% of ingested carbon bonds by cleaving preferentially after the N-terminal of aromatic amino acids such as phenylalanine and tyrosine. It will not cleave at bonds containing valine, alanine or glycine. Peptides may be further digested by other proteases (in the duodenum) and eventually absorbed by the body.
Cellulase
Cellulase refers to a class of enzymes produced chiefly by fungi, bacteria, and protozoans that catalyse the cellulolysis (or hydrolysis of cellulose). In the most familiar case of cellulase activity, the enzyme complex breaks down cellulose to beta-glucose. This type of cellulase is produced mainly by symbiotic bacteria, in the ruminating chambers of herbivores. Aside from ruminants, most animals (including humans) do not produce cellulase in their bodies, and are therefore unable to use most of the energy contained in plant material. Enzymes, which hydrolyse Hemicellulose, are usually referred to as hemicellulase and are usually classified under cellulase in general.
Lindera strychnifolia
Effects on the digestive system
Water decoction of wu yao at 1g/ml could significantly increase the amplitude of gastric electrogram in rabbits and increase the gastric contraction. Compound formula of wu yao could increase the movements of intestinal canal in anaesthetized dogs(Wen et al,. 1998).
Adhesive ileus
Supplemented Wu Yao Tang (experiential formula): wu yao, sha ren, mu xiang, xiang fu, yuan hu, and gan cao. 27 cases of adhesive were treated, 15 markedly effective, 11 improved and 2 ineffective(Wen et al,. 1998).
Bile reflux gastritis
dang shen 20g; ban xia, huang qin, chai hu, 15g each; huang lian, wu yao, zhu ru, 10g each; gan jiang 5g. Modify the formula according to TCM patterns. After 40 days’ treatment, 30 out of 32 treated cases were effective (Wen et al,. 1998).
Lonicera japonica
Esophagitis
sha shen, mai dong, gan cao, jie geng, jin yin hua, lian qiao 100g each and pang da hai 50g were made into honey pills, 1~2 pills, 3~5 times daily. 12 cases were treated, 8 were cured, 3 improved and 1 ineffective (Wen et al,. 1998).
Endothelium Corneum Gigeriae Galli
Miscellaneous effects
Ji nei jin could increase secretions of gastric mice, acidity and digestion (Wen et al,. 1998).
Infantile malnutrition
Ji nei jin 20 pieces and che qian zi 120g were dried and grounded into powder, which could be used to treat infantile malnutrition (Wen et al,. 1998).
Infantile diarrhea
Huai shan yao, fu ling, 10g each; ji nei jin 5g, ying su ke 3g (dosage for one year old children) (Wen et al,. 1998).
Duodenal ulcer
Wu zei gu, ji nei jin, bai ji, zhi shi, sheng gan cao, 100g each; yan hu suo, 50g; chen pi, 10g. All drugs were grounded into powder, 3~6g, tid. (Wen et al,. 1998).
References
Wen Weiliang, Fang Shuting, Li Chunsheng, Gao Xiaoshan, Hu Shilin, Chen Fuxin, Zhao Ronglai, Wang Junxuan, Shi Zaixiang, Su Chenlian, Lin Lan, Ye Yisen, Hu Jin, Yu Yingqi, Yu Zhenxuan, Yao Baosen, Wu Jin, Zhang Shuliang, Hou Rongxian, Kou Qiu’ai. Clinical Chinese materia medica, Henan Science & Technology Press, 1998
| Ingredients |
|---|
| Crataegus pinnatfida |
| Lonicera Japonica |
| Lindera Strychnifolia |
| Amylase |
| Protease |
| Lipase |
| Bromelain |
| Papain |
| Cellulase |
Other Ingredients: Vegetable cellulose (hypromellose); Vegetable Stearic Acid; Microcrystalline Cellulose and Vegetable Magnesium Stearate.
Does Not Contain: Wheat, gluten, soy, milk, eggs, fish, crustacean shellfish, tree nuts, peanuts
Epi-Gastro Enzyme Formula
60 x 500mg capsules
Actions
• Relieves reflux and heartburn and indigestion
• Increases gastric emptying time
• Increases pepsin and enhances protein absorption
• Helps increase gastric acid
Suggested Use:
to 3 capsules half hour prior to eating major meal. May be taken directly before a meal if irritation occurs.
Caution:
Care with internal 'cold' stomach.
Warning:
None noted.
Common Symptoms
Abdominal pain, bloating and belching after meals, chest pain, dark - tarry stools, fatigue, feeling of fullness after relatively small amounts of food, heartburn, indigestion, nausea or vomiting, especially vomiting blood & weight loss.
Alpha-amylase
Alpha-amylase begins the process of starch digestion. It takes starch chains and breaks them into smaller pieces with two or three glucose units. Two similar types of amylase are made in your body--one is secreted in saliva, where it starts to break down starch grains as you chew, and the other is secreted by the pancreas, where it finishes its job. Then, these little pieces are broken into individual glucose units by a collection of enzymes that are tethered to the walls of the intestine.
Trypsin
Trypsin is secreted into the intestine, where it acts to hydrolyse proteins into smaller peptides or amino acids. This is necessary for the uptake of protein in the food. Trypsin catalyses the hydrolysis of peptide bonds. The enzymatic mechanism is like all other serine.
Proteases
A catalytic triad serves to make the active site serine nucleophilic. This is achieved by modifying the electrostatic environment of the serine.
A lipase is a water-soluble enzyme that catalyses the hydrolysis of ester bonds in water-insoluble, lipid substrate is the main enzyme responsible for breaking down fats in the human digestive system, a lipase acts to convert triglyceride substrates found in oils from food to monoglycerides and free fatty acids.
Bromelain
Bromelain is a mixture of sulphur-containing protein digesting enzymes-called proteolytic enzymes or proteases-and several other substances in smaller quantities. Bromelain can be used in a vast array of medical conditions. It was first introduced in this area in 1957, and works by blocking some pro-inflammatory metabolites that accelerate and worsen the inflammatory process. It is an anti-inflammatory agent, and so can be used for sports injury, trauma, arthritis, and other kinds of swelling. Its main uses are athletic injuries, digestive problems, phlebitis, sinusitis, and aiding healing after surgery.
Papain
Papain is a cysteine protease (EC 3.4.22.2) present in papaya (Carica papaya), which is useful in tenderizing meat and other proteins. The mechanism by which it breaks peptide bonds involves deprotonation of Cys-25 by His-159. Asn-158 helps to orient the imidazole ring of His-159 to allow this deprotonation to take place. Cys-25 then performs a nucleophilic attack on the carbonyl carbon of a peptide backbone. This frees the amino terminal of the peptide, and forms a covalent acyl-enzyme intermediate.
Pepsin
Pepsin is a digestive protease (EC 3.4.23.1) released by the chief cells in the stomach that functions to degrade food proteins into peptides. Pepsin cleaves the 44 amino acids from pepsinogen to create more pepsin. Pepsin will digest up to 20% of ingested carbon bonds by cleaving preferentially after the N-terminal of aromatic amino acids such as phenylalanine and tyrosine. It will not cleave at bonds containing valine, alanine or glycine. Peptides may be further digested by other proteases (in the duodenum) and eventually absorbed by the body.
Cellulase
Cellulase refers to a class of enzymes produced chiefly by fungi, bacteria, and protozoans that catalyse the cellulolysis (or hydrolysis of cellulose). In the most familiar case of cellulase activity, the enzyme complex breaks down cellulose to beta-glucose. This type of cellulase is produced mainly by symbiotic bacteria, in the ruminating chambers of herbivores. Aside from ruminants, most animals (including humans) do not produce cellulase in their bodies, and are therefore unable to use most of the energy contained in plant material. Enzymes, which hydrolyse Hemicellulose, are usually referred to as hemicellulase and are usually classified under cellulase in general.
Lindera strychnifolia
Effects on the digestive system
Water decoction of wu yao at 1g/ml could significantly increase the amplitude of gastric electrogram in rabbits and increase the gastric contraction. Compound formula of wu yao could increase the movements of intestinal canal in anaesthetized dogs(Wen et al,. 1998).
Adhesive ileus
Supplemented Wu Yao Tang (experiential formula): wu yao, sha ren, mu xiang, xiang fu, yuan hu, and gan cao. 27 cases of adhesive were treated, 15 markedly effective, 11 improved and 2 ineffective(Wen et al,. 1998).
Bile reflux gastritis
dang shen 20g; ban xia, huang qin, chai hu, 15g each; huang lian, wu yao, zhu ru, 10g each; gan jiang 5g. Modify the formula according to TCM patterns. After 40 days’ treatment, 30 out of 32 treated cases were effective (Wen et al,. 1998).
Lonicera japonica
Esophagitis
sha shen, mai dong, gan cao, jie geng, jin yin hua, lian qiao 100g each and pang da hai 50g were made into honey pills, 1~2 pills, 3~5 times daily. 12 cases were treated, 8 were cured, 3 improved and 1 ineffective (Wen et al,. 1998).
Endothelium Corneum Gigeriae Galli
Miscellaneous effects
Ji nei jin could increase secretions of gastric mice, acidity and digestion (Wen et al,. 1998).
Infantile malnutrition
Ji nei jin 20 pieces and che qian zi 120g were dried and grounded into powder, which could be used to treat infantile malnutrition (Wen et al,. 1998).
Infantile diarrhea
Huai shan yao, fu ling, 10g each; ji nei jin 5g, ying su ke 3g (dosage for one year old children) (Wen et al,. 1998).
Duodenal ulcer
Wu zei gu, ji nei jin, bai ji, zhi shi, sheng gan cao, 100g each; yan hu suo, 50g; chen pi, 10g. All drugs were grounded into powder, 3~6g, tid. (Wen et al,. 1998).
References
Wen Weiliang, Fang Shuting, Li Chunsheng, Gao Xiaoshan, Hu Shilin, Chen Fuxin, Zhao Ronglai, Wang Junxuan, Shi Zaixiang, Su Chenlian, Lin Lan, Ye Yisen, Hu Jin, Yu Yingqi, Yu Zhenxuan, Yao Baosen, Wu Jin, Zhang Shuliang, Hou Rongxian, Kou Qiu’ai. Clinical Chinese materia medica, Henan Science & Technology Press, 1998